Uterine cervix is the part located at the bottom, a channel that connects the uterus with the vagina. In this area frequently found patterns of abnormal tissue growth, whether benign or malignant.One of the abnormalities that can be found is a cervical carcinoma, which is one of the most common form of malignancy in the cervix.
Cervical carcinoma is the second most common malignancy in women worldwide, and is still the leading cause of death from malignancy in women in developing countries. In the United States, cervical carcinoma is a malignant neoplasm to-4 that often occurs in women., After the malignancy of mammary, colorectal, and endometrial. The incidence of invasive cervical carcinoma has declined continuously in the United States over the past few decades, but continued to increase in developing countries.Changes in epidemiological trends in the United States is closely associated with screening large-scale with Papanicolaou tests (Pap smears).
Cervical carcinoma is a primary carcinoma originating from the cervix (the cervical canal and or porsio). Half a million cases reported annually and incidence is higher in developing countries.This is most likely not due to routine pap smear screening programs are conducted. In Latin America, the Sahara Africa, and southeast Asia, cervical carcinoma ranks first.
Course of the disease of cervical carcinoma is one model of carcinogenesis through a step or multistep, starting from the beginning to the carcinogenesis of morphological changes to become invasive carcinoma.Epidemiological studies show 90% of cervical carcinomas associated with human type papilomma virus (HPV). Some evidence suggests carcinoma with negative HPV found in older women and is associated with poor prognosis.