INDIANA, This is good news for people with cancer, particularly pancreatic cancer and cervical cancer. A number of researchers have created and tested a miniature device implanted in the center of the tumor to produce oxygen that is important to increase the killing power of radiation and chemotherapy.
The technology is designed to treat tumors that have hypoxia (oxygen deficiency) in the center of the tumor. "Radiation therapy requires oxygen to be effective," said Babak Ziaie, professor of electrical and computer engineering and biomedical engineering at Purdue University, Indiana, United States, such as broadcast ScienceDaily, Wednesday (31 / 8) or Thursday (09/01/2011) pm.
"It's hard to kill pancreatic cancer and cervical cancer are well known due to hypoxia (at the cancer center). If you produce oxygen, you can increase the effectiveness of radiation therapy and chemotherapy as well."
Tool called "oxygen generator implanted micro" is an electronic device that receives the signal and uses ultrasound energy to produce a small voltage to separate oxygen and hydrogen from water. Chemical activity of water is called electrolysis.
"We put this device inside tumors and then exposing the tumor (cancer) with ultrasound," said Ziaie. "
The strength of the ultrasound energy will raise the device, to then produce oxygen." The device was created at the Birck Nanotechnology Center at Purdue University's Discovery Park. Purdue University researchers worked with Song-Chu (Arthur) Ko, assistant clinical professor of radiation oncology at Indiana University School of Medicine.
The researchers have tested the device on pancreatic tumors implanted in mice. Experiments that produce oxygen and the tumors shrank faster than tumors without the device. The length of the device is slightly less than one centimeter, and inserted into the tumor with a syringe. "Most of us have been touched by cancer in one way or another," said Ziaie.
"My father is a survivor (survivor) cancer, and he went through many rounds of chemotherapy is very painful. (Tool) is a new technology that has the potential to improve the effectiveness of such therapy."A patent application has been filed for the design of these devices.However, future work is to redesign the device to make it more practical for manufacturing and clinical trials.
Tool called "oxygen generator implanted micro" is an electronic device that receives the signal and uses ultrasound energy to produce a small voltage to separate oxygen and hydrogen from water. Chemical activity of water is called electrolysis.
"We put this device inside tumors and then exposing the tumor (cancer) with ultrasound," said Ziaie. "
The strength of the ultrasound energy will raise the device, to then produce oxygen." The device was created at the Birck Nanotechnology Center at Purdue University's Discovery Park. Purdue University researchers worked with Song-Chu (Arthur) Ko, assistant clinical professor of radiation oncology at Indiana University School of Medicine.
The researchers have tested the device on pancreatic tumors implanted in mice. Experiments that produce oxygen and the tumors shrank faster than tumors without the device. The length of the device is slightly less than one centimeter, and inserted into the tumor with a syringe. "Most of us have been touched by cancer in one way or another," said Ziaie.
"My father is a survivor (survivor) cancer, and he went through many rounds of chemotherapy is very painful. (Tool) is a new technology that has the potential to improve the effectiveness of such therapy."A patent application has been filed for the design of these devices.However, future work is to redesign the device to make it more practical for manufacturing and clinical trials.
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